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In this study PRP positively regulated MIIP levels and
2024-10-31
In this study, PRP4 positively regulated MIIP levels and significantly inhibited the invasion of HCT116 cells. Further investigations elucidated that PRP4 dephosphorylated MIIP via PP1A regulation, which was confirmed by PP1A inhibition in the presence of OA. Upon dephosphorylation, MIIP possibly in
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br Acknowledgments We thank the anonymous reviewers for thei
2024-10-31
Acknowledgments We thank the anonymous reviewers for their constructive comments on the manuscript, and also thank Dr. Hans-U. Dahms for his comments on the manuscript. This work was supported by a grant from the National Research Foundation (2009-0071218) funded to Young-Mi Lee. This work was al
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Firms are subject to corporate taxation and face either
2024-10-31
Firms are subject to corporate taxation, and face either an ACE or a CBIT tax scheme. The two tax regimes achieve financing neutrality by treating debt and equity equally, but differ according to whether deduction of capital costs from the corporate tax 3230 synthesis is allowed or not. While ACE al
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Eicosanoids are locally acting signaling lipids that are pro
2024-10-31
Eicosanoids are locally acting signaling lipids that are produced from C20 polyunsaturated fatty acids (PUFAs), including arachidonic Amprolium HCl (AA, C20:4), eicosapentaenoic acid (C20:5) and eicosatrienoic acid (C20:3) (Dennis and Norris, 2015; Funk, 2001; Stables and Gilroy, 2011). According to
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br Phosphorylation of P c Initial studies In addition to
2024-10-31
Phosphorylation of P450c17 – Initial studies In addition to the molar ratio of POR to P450c17 and the allosteric action of cytochrome b5, a third factor that governs 17,20 lyase activity is the serine/threonine (Ser/Thr) phosphorylation of P450c17 itself. In a search for post-translational factor
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There is little question that as we
2024-10-30
There is little question that as we become more proficient in the diagnosis of arginase 1 deficiency individuals with intermediary elevations in arginine on newborn screening and partial defects in enzymatic activity will be found. There are no reliable data to determine a safe level of arginine and
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In our previous report salivary arginase
2024-10-30
In our previous report, salivary arginase levels were found to be higher in periodontitis patients compared to healthy controls (Ozmeriç, Elgün, & Uraz, 2000). However, only one study has investigated arginase ezyme in saliva in patients with dental implants in which smokers were also included. An i
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Citral or dimethyl octadien al is a mixture of two
2024-10-30
Citral or 3,7-dimethyl-2,6-octadien-1-al is a mixture of two stereoisomeric monoterpene aldehydes (the trans isomer geranial, citral A (40–62%)) and the cis isomer neral, citral B (25–38%) and serves one of the main constituent of essential oils of C. citratusis used in cosmetic, food, fungicides, p
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It was deduced empirically that
2024-10-30
It was deduced empirically that the helix direction of the COOC torsion might relate to the sign of the peroxide Cotton effect. Huang reported ab initio calculation of the peroxide bond using MRDCI method and DZP basis set, but only the fragment CH3OOCH3 instead of full molecule was studied [19]. S
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449 synthesis br Introduction Alzheimer s disease AD is
2024-10-30
Introduction Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia. It is characterized by progressive and irreversible damage to different 449 synthesis areas, resulting in cognitive impairment and behavioral changes (O'Neill, 2013, De Strooper and Karran, 2
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The ORR obtained with crizotinib on our cohort was low
2024-10-30
The ORR obtained with crizotinib on our cohort was low compared to other studies, such as the prospective studies of A. Shaw et al. (ORR = 65% in second line), B. Solomon et al. (ORR = 74% in first line) and the more comparable large retrospective study of M. Duruisseaux et al. on the French CLINALK
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Tropomyosi http www apexbt com media diy images
2024-10-30
Tropomyosin-related kinases (Trks) play crucial role in neurotrophin-mediated cellular activities, including neuronal differentiation, survival, and synaptic function [37] through activating downstream signaling mediators PI3K and Akt [38]. In a therapeutic context, Akt has been shown to mediate str
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There are two ways to
2024-10-30
There are two ways to transport FFAs into cells. First by passive diffusion. Second as the putative long-chain fatty 2-Palmitoylglycerol transporters are proposed, CD36 the plasma membrane-associated fatty acid-binding protein (FABPpm) and fatty acid transport proteins (FATP) [11], where CD36 is re
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Since non lipoprotein derived free cholesterol is recycled
2024-10-30
Since non-lipoprotein-derived free cholesterol is recycled from the plasma membrane through the endosomal system through receptor-independent mechanisms, we wanted to determine whether ABCA2 could alter the trafficking of this source of free cholesterol. Our approach was to measure the effect of mob
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Introduction Diabetic nephropathy is a rapidly growing
2024-10-30
Introduction Diabetic nephropathy is a rapidly growing cause of end-stage renal disease [1]. Glomerular, tubular and vascular toxicity resulting from hyperglycemia (glucotoxicity) have been evaluated extensively at the molecular level as contributing factors for diabetic nephropathy [[1], [2], [3]]
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